Home / The Curbsiders Internal Medicine Podcast / #498 Opioid Withdrawal with Dr. Ashish Thakrar

#498 Opioid Withdrawal with Dr. Ashish Thakrar

The Curbsiders Internal Medicine Podcast

Sep 15, 2025

1h 17m

Description

Grow your management tools for opioid withdrawal in the hospital. Investigate how to decide between methadone and buprenorphine, additional medications to manage symptoms and how and when to use short-acting opioids for management of withdrawal. We’re joined by Ashish Thakrar, MD at the University of Pennsylvania.

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By listening to this episode and completing CME, this can be used to count towards the new DEA 8-hr requirement on substance use disorders education.

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Show Segments

Intro, disclaimer, guest bio

Guest one-liner

Case from Kashlak; Definitions

Symptoms of opioid withdrawal

Medications for the management of opioid withdrawal

Buprenorphine precipitated withdrawal

Starting Buprenorphine: Experiences and Strategies

Titrating Methadone: Dosage and Adjuncts

Adjunctive short-acting opioids

Emerging Trends in Drug Supply: Xylazine and Medetomidine

Outro

Credits

Producer, Show Notes: Zina Huxley-Reicher

Infographics: Zina Huxley-Reicher MD and Zoya Surani

Hosts: Carolyn Chan, MD MHS, Zina Huxley-Reicher MD, Shawn Cohen, MD

Reviewer: Payel Jhoom Roy, MD, MSc

Showrunner: Carolyn Chan, MD, MHS

Technical Production: PodPaste

Guest: Ashish Thakrar, MD MHSP

Sponsor: Mint Mobile

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Sponsor: Freed

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